The Relationships between Leptin and Measures of Fitness and Fatness Are Dependent upon Obesity Status in Youth

Peter A. Hosick, Robert G. McMurray, Dan M. Cooper
2010 Pediatric Exercise Science  
The relationships between leptin and measures of fitness and fatness are dependent upon obesity status in youth. Permalink https://escholarship.org/uc/item/0hk772qs Journal Pediatric exercise science, 22 (2) The relationship between peak aerobic fitness (peakVO 2 ) and plasma leptin was assessed in 25 normal (BMI < 85th %tile) and 25 overweight (BMI > 85th %tile) youth, ages 7-17 years. In the overall analysis peakVO 2 was related to leptin when expressed in mL/kg/min (R 2 = .516, p < .0001),
more » ... .516, p < .0001), or as ml/kg FFM /min (R 2 = .127, p = .01). The relationships between peakVO 2 and leptin were no longer significant when percent bodyfat was added to the models. In subanalyses by weight groups, peakVO 2 : leptin relationships were not evident for normal weight, but remained for overweight youth. In conclusion the relationship between aerobic fitness and leptin in youth is dependent upon weight status. Hosick and McMurray are with the
doi:10.1123/pes.22.2.195 pmid:20567041 fatcat:hyjymwhxxvdr3pxxtkwympidje