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Carbapenem resistantEnterobacteriaceae(CRE) have emerged as a critical public health threat. Organisms expressing theKlebsiella pneumoniaecarbapenemase (KPC) were first recognized in the US in the late 1990s and continue to be the predominant CRE genotype reported in clinical isolates. Strains harboring blaKPCalleles have been observed in multiple species ofEnterobacteriaceae, including theEnterobacter cloacaecomplex. A majorE. cloacaeclone,Enterobacter xiangfangensisST171, has emerged as andoi:10.1101/337428 fatcat:ipvu7hfk5fc6zftj74qmfbkb6q