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Dengue is a serious public health problem that has neither vaccine nor specific treatment. Serology is the most frequently used diagnosis method, specifically the anti-dengue IgM detection. The viral antigens employed in this method could be prepared from Aedes albopictus cell cultures (C6/36). The objective of this study was to maintain the four viral serotypes [D1 (RIO), D2 (RIO), D3 (H-87), D4 (BV)] on C6/36 cells for the preparation of viral antigen in the future. The C6/36 cells weredoaj:82a14c3f06e84c8aa3523bd1a59252bc fatcat:wi3cxxyxtrhnnn47h6opuhxwfi