Synthesis , identification and evaluation of antibacterial activity for some new heterocyclic derivatives from 4-methoxy-2-nitroaniline

Sabah Matrood Mezaal, Shaimaa Adnan
2021 Al-Qadisiyah Journal Of Pure Science  
This research involved synthesis. novel heterocyclic derivatives (quinazoline and thiazinone) derivatives , this compounds prepared from starting react (4-methoxy-2-nitroaniline) with 2,4-dimethoxyacetophenone to gate azo derivative (A) , (A) interact with aromatic amine derivatives to produce imine compounds (B1-B2), imine derivatives interact with (anthranilic acid , 2-mercaptobenzoic) to get heterocyclic derivatives quinazoline (C1-C2) and thiazinone (D1-D2 ) . All these compound
more » ... d by13 C-NMR , FT-IR , 1HMNR . Then that,we studies the,biological,properties for,all heterocyclic derivatives,to,ward.two different kindof bacteria.
doi:10.29350/qjps.2021.26.4.1383 fatcat:bp5q4ufuzvbnjooz4yahb2x6lq