Comparison of Cotinine Salivary Levels between Smokers : Smokers and Non-Smokers Passive
The Egyptian Journal of Hospital Medicine
Cotinine is the predominant metabolite of nicotine which found in tobacco. At present, smoking cigarettes and hookah are on the rise in the Middle East countries; therefore, the number of people exposed to passive cigarette smoking is increasing too. Objective: To compare the salivary cotinine level in saliva in smokers, non-smokers, passive smokers. Also to combat the wrong opinion that hookah is not harmful. Material and methods: In this cross-sectional study, unstimulated salivary samples
... salivary samples were collected from 30 female subjects including students and workers at College of Dentistry, Umm Al-Qura university, Makkah. The study participants were divided into 3 groups (each of 10 subjects) aged 19-50 years; o First group: with history of cigarettes or hookah smoking at least one session/day for 20-30 minutes for at least 2 years. o Second group: exposed to cigarette smoke or hookah. o Third group: non-smoker. TheNicAlert™ (NYMOX pharmaceutical corporation, Canada) nicotine saliva test was used to determine salivary levels of cotinine. Results: Salivary cotinine level was detected in all study groups with the different levels. The highest level was in a group of smokers while 50% of non-smokers showed level one. There were no significant differences in salivary cotinine levels between hookah, cigarette and both smokers and a significant relation between duration and salivary cotinine level.Also a non-significant relation was found between age and salivary cotinine level. Conclusion: Salivary cotinine levels were higher in smokers compared to passive smokers and non-smokers, in descending order.