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Changes in phenotype and phenotypic flexibility of alveolar macrophages in inflammatory pulmonary diseases
2012
Russian Pulmonology
We studied phenotypic specificity and flexibility of innate immunity cells, such as alveolar macrophages isolated from bronchoalveolar lavage fluid (BALF) in patients with chronic obstructive pulmonary disease (COPD), bronchial asthma (BA) and sarcoidosis which are lung diseases with inflammatory component. We found that M1 macrophages prevailed in COPD and sarcoidosis patients and M2 macrophages prevailed in BA patients though the macrophage populations were not monophenotypic. The
doi:10.18093/0869-0189-2012-0-6-83-89
fatcat:nrosh3zlqbcutobuidlljueehe