CdSe quantum dots evaluation in primary cellular models or tissues derived from patients

Carlota Tosat-Bitrián, Valle Palomo
2020 Nanomedicine: Nanotechnology, Biology and Medicine  
In recent years Quantum Dots (QDs) have risen as useful luminescent nanoparticles with multiple applications ranging from laser, image displays and biomedical applications. Here we review and discuss the studies of these nanoparticles in patient derived cellular samples or tissues, including cellular models from iPSCs from patients, biopsied and post-mortem tissue. QD-based multiplexed imaging has been proved to overcome most of the major drawbacks of conventional techniques, exhibiting higher
more » ... ensitivity, reliability, accuracy and simultaneous labelling of key biomarkers. In this sense, QDs are very promising tools to be further used in clinical applications including diagnosis and therapy approaches. Analyzing the possibilities of these materials in these biological samples gives an overview of the future applications of the nanoparticles in models closer to patients and their specific disease.
doi:10.1016/j.nano.2020.102299 pmid:32931928 fatcat:7xhi3udrmze75cjz7oivb6oijm