Naturally coumarins have some bioactivity and commonly used among traditional medicine recipes against diabetes and hepatitis diseases. In addition to their derivatives that possess high importance due to their biological activity, therefore they are induced in the pharmaceutical industry as anticoagulant, antimicrobial, antiinflammatory, antiviral, antioxidant and analgesic compounds. In this study, the formation of coumarin derivatives, which involved in pharmaceutical industries, was passed

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... hrough by studying their method of preparation, mechanism of their preparative reactions and the study of their rate of reactions. Reactions were demonstrated subsequently by obtaining the product to be obtained for the next one and starting from coumarin synthesis.