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Kinetics of the Inhibitory Effect of Factor IXBm in the Activation of Factor X by Factor VII and Bovine Tissue Factor
1979
VIIth International Congress on Thrombosis and Haemostasis
unpublished
F.IXBm is giving a prolonged prothrombin time with bovine tissue factor (T.F.). In the present study the inhibitory effect of purified F.IXBm was tested in a F.VII assay that measures the ability of F.VII to activate F.X in the presence of bovine T.F. and Ca++, followed by the quantitation of formed F.Xa by the synthetic substrate benzoyl -L-Ile-Glu-Gly-L-Arg-p-nitroanilide. Experiments were carried out with different concentrations of F.IXBm and F.X, keeping the concentrations of F.VII and
doi:10.1055/s-0039-1684667
fatcat:iawase55ibagzod4fqwgfkxemy