Multi-contrast photoacoustic microscopy

S. Hu, R. Sohn, Z.-H. Lu, B. Soetikno, Q. Zhong, J. Yao, K. Maslov, J. M. Arbeit, L. V. Wang, Alexander A. Oraevsky, Lihong V. Wang
2012 Photons Plus Ultrasound: Imaging and Sensing 2012  
We developed multi-contrast photoacoustic microscopy (PAM) for in vivo anatomical, functional, metabolic, and molecular imaging. This technical innovation enables comprehensive understanding of the tumor microenvironment. With multi-contrast PAM, we longitudinally determined tumor vascular anatomy, blood flow, oxygen saturation of hemoglobin, and oxygen extraction fraction.
doi:10.1117/12.909754 fatcat:iste2gbmanf3xc45fpmn766m2u