and Aims: Studies have not been able to prove an association between allergy and Helicobacter pylori (H. pylori) infection. The goal of this study is to evaluate the association of total immunoglobulin E (IgE) level, as a criterion for the presence of allergy, and H. pylori infection. Methods and Materials: Seventy two patients with dyspepsia referring to endoscopy were included in this study. Anti-H. pylori IgG, anti-H. pylori-CagA IgG, and total plasma IgE levels were measured using enzyme

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... ked immunosorbent assay and then statistically analyzed. Results : Forty out of 72 patients had H. pylori infection, out of which 32 patients were CagA positive. Mean IgE level had a significant increase in the patients with H. pylori infection (p<0.05), but there was no significant difference between IgE levels of the CagA-positive and -negative groups (p=0.175). Conclusion: Our study demonstrated a clear association between allergy and H. pylori infection.