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Human anthrax infection caused by exposure toBacillus anthraciscannot always be treated by antibiotics. This is mostly because of the effect of the remaining anthrax toxin in the body. Lethal factor (LF) is a component of lethal toxin (LeTx), which is the major virulence of anthrax toxin. A murine IgG monoclonal antibody (mAb) against LF with blocking activity (coded LF8) was produced in a previous study. In this report, a human/murine chimeric Fab mAb (coded LF8-Fab) was developed from LF8 bydoi:10.1155/2013/475809 pmid:23861692 pmcid:PMC3687597 fatcat:enwlcfvh2jg2talqdcrnmqavhq