Heart, Myocardial Oxygen Consumption, Fifteen Minutes Perfusion. Four extracorporeal perfusion conditions (continuous beating, continuous fibrillating, pulsatile beating, pulsatile fibrillating) were tested for 15 minutes each in dogs. Coronary flow, myocardial oxygen consumption and hemodynamics were measured. No significant hemodynamic differences in any of these variables were found between pulsatile and continuous flow states in either fibrillating or beating hearts. In both fibrillating

more »

... ditions, significant elevations of myocardial oxygen consumption by continuous perfusion were found (P<0.01). These data suggest caution in the expection that pulsatile perfusion will reverse myocardial oxygen consumption changes seen with fibrillation.