Cerebellar hypoplasia in an Azawakh dog: A case report

Pelin Fatoş POLAT, Gürbüz AKSOY, Rabia ALTUNTAŞ, İsmail ÇETİNTAŞ
2020 Journal of Advances in VetBio Science and Techniques  
In this case report, a nine-month-old male Azawakh dog was observed for ataxia, uncoordinated movements, and difficulties in walking and standing, intensive head tremors, trouble evacuating and eating. It was determined to have mild cerebellar hypoplasia in MR imaging and symptomatic treatment was started with glucocorticoids, vitamin B 1 , B 6 and diazepam. But these drugs had no effectiveness on the symptoms and the dog died three weeks later. In the necropsy macroscopic cerebellar reduction
more » ... rebellar reduction was determined and cerebellum and granular cell hypoplasia was indicated histopathologically. Immunohistochemically, the atrophy of neuronal cells showing positive staining with anti-GFAP antibody and vacuolar degeneration were identified. Based on clinical findings, MR imaging, histopathological and immunochemical findings, cerebellar hypoplasia was diagnosed in the dog and this study is the first case detected in an Azawakh dog.
doi:10.31797/vetbio.622632 fatcat:4w4omplzqvezfpxspl7qat7w7y