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Histopathological Study of the Effect of Periodontopathic Bacterial Lipopolysaccharide on Changes in Rat Periodontal Tissue after Penetration through the Gingival Sulcus
Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology)
This study was performed to clarify the in vivo damage to periodontal tissue induced by lipopolysaccharide (LPS) from Actinobacillus actinomycetemcomitans Y 4 and Porphyromonas gingivalis 381, which penetrate the junctional epithelium. Each LPS solution (5 mg/ml) was continuously dropped into the gingival sulcus of the lower first molar of a Lewis rat for 30min every 24h.doi:10.2329/perio.40.198 fatcat:z7hjvwd67ne6ngcqmyxbxex474