The COVID-19 Drug and Gene Set Library

Maxim V. Kuleshov, Daniel J. Stein, Daniel J.B. Clarke, Eryk Kropiwnicki, Kathleen M. Jagodnik, Alon Bartal, John E. Evangelista, Jason Hom, Minxuan Cheng, Allison Bailey, Abigail Zhou, Laura B. Ferguson (+2 others)
2020 Patterns  
Graphical Abstract Highlights d Collections of drug and gene sets relevant to COVID-19 research d Detailed comparison of results from six in vitro SARS-CoV-2 drug screens d Analysis of hits that up-or downregulate the ACE2 expression module d Machine-learning framework to further prioritize hits and other similar drugs
doi:10.1016/j.patter.2020.100090 pmid:32838343 pmcid:PMC7381899 fatcat:ef7ph4xztzcyfesgrfrt3jjuyq