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We study the level of image artifacts in optical tomography associated with measurement uncertainty under three reconstruction configurations, namely, by using only direct-current (DC), DC-excluded frequency-domain, and DC-included frequency-domain data. Analytic and synthetic studies demonstrate that, at the same level of measurement uncertainty typical to optical tomography, the ratio of the standard deviation of μ a over μ a reconstructed by DC only is at least 1.4 times lower than that bydoi:10.1364/ao.49.003059 pmid:20517376 fatcat:gkredvxlbnhxfidaohczsxx6ki