Nowadays the use of insecticides are used in households to control many kind of insects that are vectors of desease. High-intensity insecticide exposure can cause poisoning and other adverse health effects. Insecticide handling behavior is one of the determinant factors of exposure intensity.The objective of this study was to analyze determinants of household insecticide handling practices in the Indralaya Ogan Ilir District. An observational analytical study with a cross-sectional approach was

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... carried out using cluster sampling. The study involved 150 housewives who have used insecticides in their households. Data was collected through interviews using questionnaires and observations using a checklist . Processing data was performed using software . Data were analyzed using a Chi-Square test with a 0.05 significance level. Research results showed there was a significant association between age and handling behavior of household insecticides (p=0.006). Also, education level significantly correlated to household insecticide handling practices (p=0.05); marital status correlated to household insecticide handling practices significantly (p=0.028). Significant association was also found between attitudes regarding handling behavior of household insecticides (p=0.035). On the other hand, employment status (p=0.165), socioeconomic status (p=1.000), knowledge (p=0.796), counseling (p=0.472) and insecticide waste disposal facilities (p=0.331) were not associated with handling behavior of household insecticides. It is concluded that there were significant associations between age, education level, marital status, and attitudes regarding handling behavior of household insecticides (Chi-Square test, all p≤0.05). However, employment status, socioeconomic status, knowledge, counseling, and insecticide waste disposal facilities were not associated with handling behavior of household insecticides (Chi-Square test, all p>0.05). Keywords: household insecticide , knowledge, attitude, handling behavior