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Malignancies related mortality is currently growing at an alarming rate. Early detection of cancer is vital in order to improve survival rates of cancer patients, and biomarker detection is regarded as one of the most promising approaches. Recent studies have reported that elevated AMPK-related kinase 5 (ARK5) expression is associated with tumor progression and metastasis in several human malignancies. Several pathways are also influenced by the presence of ARK5, most notably the PI3k-Aktdoi:10.15419/bmrat.v6i10.568 fatcat:txfxkvwkuzgefn7yi7vntwmy7e