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Analysis of protein microarrays by FTIR imaging
Biomedical Spectroscopy and Imaging
BACKGROUND: Proteins are sensitive to environmental conditions. Whether they are produced for therapeutic purposes or for fundamental research, the integrity of their structure and post-traductional modifications are key issues. Measuring glycosylation or phosphorylation level as well as their secondary structure most often rely on complex and indirect experiments. Infrared spectroscopy presents a series of advantages related to its multivariate character. There is a lack of high-throughputdoi:10.3233/bsi-160137 fatcat:66qh6k2d7jdq5dd2ua4w54ni2q