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Primary objective-Paroxysmal sympathetic hyperactivity (PSH) is observed in a sub-set of patients with moderate-to-severe traumatic brain injury (TBI). The neuroanatomical basis of PSH is poorly understood. It is hypothesized that PSH is linked to changes in connectivity within the central autonomic network. Research design-Retrospective analysis in a sub-set of patients from a multi-centre, prospective cohort study Methods and procedures-Adult patients who were <3 weeks after severe TBI weredoi:10.3109/02699052.2014.995229 pmid:25565392 pmcid:PMC4397147 fatcat:47rxubkwdfee7c4zbyzf3372pe