Adding а thiazide diuretic to combined antihypertensive therapy is clinically reasonable

V. I. Makolkin
2008 CARDIOVASCULAR THERAPY AND PREVENTION  
The article describes the reasons for including thiazide and thiazide-like diuretics into combined antihypertensive therapy, with a combination of a beta-adrenoblocker (BAB) bisoprolol and a thiazide diuretic (TD) hydrochlorothiazide as an example. Diuretics should be administered in the doses not affecting glucose tolerance and lipid metabolism. Using Lodoz® medication as an example, the author stresses the need for combining D with various BAB doses, which could increase therapeutic potential
more » ... while administering combined antihypertensive therapy.
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