Vascular Response after Directional Coronary Atherectomy for Left Main Bifurcation Lesion [post]

Norihiro Kobayashi, Masahiro Yamawaki, Mana Hiraishi, Shinsuke Mori, Masakazu Tsutsumi, Yohsuke Honda, Toshiki Chishiki, Kenji Makino, Shigemitsu Shirai, Masafumi Mizusawa, Kohei Yamaguchi, Takahide Nakano (+4 others)
2021 unpublished
Purpose: To evaluate the vascular response after directional coronary atherectomy (DCA) for left main (LM) bifurcation lesion.Methods: This study was a retrospective, single-center study enrolling 31 patients who underwent stent-less therapy using DCA followed by drug-coated balloon angioplasty for LM bifurcation lesion. We compared the intravascular ultrasound (IVUS) findings pre- and post DCA. Results: After DCA, the lumen and vessel areas significantly increased whereas the plaque area (PA)
more » ... nd %PA significantly decreased. When the lesions were divided into small and large vessel groups using the median vessel area value, the maximum balloon pressure of the DCA catheter was greater in the large than in the small vessel group. Changes in the lumen and vessel areas were also significantly greater in the large than in the small vessel group. Conversely, the PA and %PA changes were similar between the groups. Conclusion: The main vascular responses associated with lumen enlargement after DCA were plaque reduction and vessel expansion. Contribution of vessel expansion to lumen enlargement was larger than the effect of plaque reduction in large than in small-vessel lesions.
doi:10.21203/rs.3.rs-655491/v1 fatcat:hjfbj4thnreblhcde4lidpwgv4