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Acute leukemia is characterized by the presence of 20% or more blasts in peripheral blood and/or bone marrow biopsy. It includes both AML & Acute ALL. However the diagnosis of AML can also be made when the blast percentage in peripheral blood or bone marrow is < 20 % if there is an associated t (8;21), inv ( 16 ), or t (16;16) chromosomal abnormality or PML-RAR fusion gene    . Tumor lysis syndrome is the most common disease related emergency in patients with leukemia & requires immediate management.doi:10.21089/njhs.42.0067 fatcat:5ev2jfwonnaczjrji6a7v5qnoy