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It is the Locus Coeruleus! Or… is it? : A proposition for analyses and reporting standards for structural and functional magnetic resonance imaging of the noradrenergic Locus Coeruleus
AbstractThe noradrenergic locus coeruleus (LC) in the brainstem shows early signs of protein pathologies in neurodegenerative diseases such as Alzheimer's and Parkinson's disease. As the LC's small size (approximately 2.5 mm in width) presents a challenge for molecular imaging, the past decade has seen a steep rise in structural and functional Magnetic Resonance (MR) studies aiming to characterise the LC's changes in ageing and neurodegeneration. However, given its position in the brainstem anddoi:10.1101/2021.10.01.462807 fatcat:75fk3kjyofek3ky3mbcj7xkuli