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Catalyst-Free Selective C5-H Bromination and Chlorination of 8-Amido Quinolines
2017
Youji huaxue
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A simple and efficient selective halogenation (Cl, Br) reaction in the C5 position of 8-amidoquinolines has been developed via catalyst free C-H bond elaboration. This facile synthetic method shows good substrate tolerance and most of the halogenated products were obtained with excellent yield.
doi:10.6023/cjoc201705041
fatcat:q6deohgdmrbstge4xudabxxufq