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Oral thearubigins do not protect against acetaminopheninduced hepatotoxicity in mice
2016
Tropical Journal of Pharmaceutical Research
Purpose: To investigate the potential protective effect of oral repeated doses of thearubigins against acetaminophen-induced hepatotoxicity in mice. Methods: Mice were randomly divided into six groups (n=8) and administered the following: Control group (saline), acetaminophen group (saline), N-acetylcysteine group (500 mg/kg/day), and thearubigins groups (60, 70, 100 mg/kg/day). The drugs were given orally by gavage for seven days. On day 7, 1 h after the last dose of treatment, the mice
doi:10.4314/tjpr.v15i9.14
fatcat:4tebwnzqxveg5p4zfwolzz237a