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The effects of tumor‐derived exosomes on T‐cell function and efficacy of cancer immunotherapy
2021
Immunomedicine
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Tumor-derived exosomes (TEXs) are a class of extracellular vesicles which play an important role in the tumor microenvironment. These vesicles have multiple biological functions including promotion of cancer progression and reduction of anti-tumor immunity. Recently, interaction between TEXs and immune cells are of great interest in cell-based immunotherapy. Here, we review the effects of TEXs on the survival and functions of T cell subsets, as well as their clinical applications. Unraveling
doi:10.1002/imed.1029
fatcat:axrweghobbadzmwjahplvrsh3y