The human genome has various genomic regions that can create a large number of transcripts. RNAs that can function as both mRNA and noncoding RNA (lncRNA/snoRNA/miRNA) are known as bifunctional RNAs, or bifRNAs. BifRNAs have been detected in everything from microorganisms to humans. Cells may accurately modify the functions of the coding and noncoding regions of bifRNAs to satisfy relevant regulatory needs. However, it has not been thoroughly investigated whether the same gene locus may produce

more »

... two types of functional nc transcripts, such as lncRNAs and miRNAs. These "bifunctional nc RNAs" are the topic of this review. This evaluation contained all the current information regarding LncMIRHGs. Some LINC MONOMER transcripts have not been proven to be "junk" according to this functional and mechanistic research. It is possible that the lncMIRHG locus makes both functional miRNAs and lncRNAs, some of which can act together and others of which may act independently. The data gathered via research by the NEAT1 organization also indicates that miRNA may function as a "pseudoRNA," with lncRNA produced from the lncMIRHG gene locus serving as the lead. A significant amount of focus on this class of lncRNAs must be given since the beauty of the lncMIRHG loci, which control these putative dual functions as lncRNA and miRNA, strongly recommends that we should do so. LincMIRHGs are utilized in a broad number of tasks, including those seen in disorders like cancer. It will be useful for medicine creation and development to have a full understanding of this lncRNA repertoire's mechanisms.