The 16th Congress of the Mediterranean Phytopathological Union (MPU2022) took place in Limassol, Cyprus from 4–8 April, 2022. Plant pathologists from the region and beyond celebrated the 60th anniversary of the Union and the 62 years of publication of Phytopathologia Mediterranea as a top level plant pathology journal. MPU2022 entitled "Safeguarding Mediterranean Plant Health" promoted dissemination of the latest scientific advances, and facilitated dialogue and collaboration between

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... interested in all aspects of Phytopathology. This conference also addressed wider perspectives in scientific fields not previously explored at MPU Congresses, including abiotic stresses, biopesticides, forest pathology, smart agriculture and gender equality in research, funding, teaching and professional development. Papers presented at the Congress included 83 oral presentations, including 15 keynote presentations from leading scientists, and 63 poster presentations, covering all areas of plant pathology and plant stress research, from 130 participants. Five special sessions in cutting edge subjects were organised. A special session was organised jointly with the Arab Society of Plant Protection. All these scientific contributions are part of this issue.