Insulin Autoimmune Syndrome after the Third Therapy with Methimazole

Mutsumi HAKAMATA, Mitsuyasu ITOH, Yuichiro SUDO, Norikazu MIYATA
1995 Internal medicine (Tokyo. 1992)  
In 1986, a 26-year-old female had been diagnosed as having Graves' disease and had been treated with methimazole for four months. After the treatment with propylthiouracil for another four months, she had been treated with methimazole once again. She was in complete remission for two years. She again experienced symptomsof hyperthyroidism, and treatment with methimazole was started again. Onthe thirteenth day after treatment, she experienced hypoglycemic attacks with skin eruption. The plasma
more » ... ucose was 57 mg/dl, 125I-Insulin binding 69%, free IRI 196 |iU/ ml. The patient had the HLA-DRBl*0406. (Internal Medicine 34: 410-412, 1995)
doi:10.2169/internalmedicine.34.410 fatcat:schi7tby7rem3evs3yj2bctxd4