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RNA at the surface of phase-separated condensates impacts their size and number
Membrane-less organelles, by localizing and regulating complex biochemical reactions, are ubiquitous functional subunits of intracellular organization. They include a variety of nuclear and cytoplasmic ribonucleoprotein (RNP) condensates, such as nucleoli, P-bodies, germ granules and stress granules. While is it now recognized that specific RNA and protein families are critical for the biogenesis of RNP condensates, how these molecular constituents determine condensate size and morphology isdoi:10.1101/2021.06.22.449254 fatcat:p7xqzcxu7zhipmaqvxfq7d57wu