Association between epicardial fat thickness and cognitive function in elderly. A preliminary study

Walter Verrusio, Alessia Renzi, Valerio Massimo Magro, Marco Musumeci, Paola Andreozzi, Mauro Cacciafesta
2019 Annali dell'Istituto Superiore di Sanità  
Recent studies suggested that the visceral fat could exert a predictive role in the pathogenesis of dementia. The aims of the present study were to evaluate: i) possible differences between groups with different epicardial adipose tissue (EAT) thickness on the included variables; ii) the possible predictive role of the EAT levels on cognitive functioning. 65 community-dwelling subjects were enrolled and divided into two groups: EAT < 7 mm (n = 36); EAT > 7 mm (n = 29). The metabolic profile was
more » ... assessed through the evaluation of the biochemical parameters whereas the EAT thickness was measured through the transthoracic echocardiography. The Mini Mental State Examination (MMSE) was also administered. The two EAT groups reported several significant differences, included on the MMSE scores. The multiple linear regression analysis showed that the EAT thickness levels and the hypertension had a predictive effect on the MMSE scores. These preliminary findings support the association between EAT thickness levels and cognitive impairment.
doi:10.4415/ann_19_01_11 pmid:30968838 fatcat:vssv6xsik5bvfkhkj3rdcziyoq