Conclusion Although an important proportion of SLE pregnancies result in live birth, active disease, especially renal and NP involvement, and damage increase the risk of complications. Furthermore, the presence of APS or antiphospholipid antibody positivity are important risk factors for APO. In conclusion, patients, especially with damage, should be pre-counselled to be made aware of the risks. Pregnancy should be allowed after disease activity is controlled and a close monitoring with O&G clinics is essential.