We analyzed the basic hazard characteristics for isoprene in the manufacturing process by evaluating the runaway reaction, kinetic parameters and safety parameters in this study. Experiments were carried out by calculating the thermal decomposition reactions for isoprene and mixed with aluminum oxide in non-isothermal conditions by differential scanning calorimetry (DSC). Afterwards results indicated that isoprene had a conjugated double bond of unstable structure, and therefore it was prone to

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... produce exothermic reaction during the process of polymerization. Aluminum oxide was applied to mix with isoprene, which could increase the heat release rate. Based on the results, safety information should be provided to government and relevant industries for prevention the accident occur in relevant plants.