OCT angiography by absolute intensity difference applied to normal and diseased human retinas

Daniel Ruminski, Bartosz L. Sikorski, Danuta Bukowska, Maciej Szkulmowski, Krzysztof Krawiec, Grazyna Malukiewicz, Lech Bieganowski, Maciej Wojtkowski
2015 Biomedical Optics Express  
We compare four optical coherence tomography techniques for noninvasive visualization of microcapillary network in the human retina and murine cortex. We perform phantom studies to investigate contrast-to-noise ratio for angiographic images obtained with each of the algorithm. We show that the computationally simplest absolute intensity difference angiographic OCT algorithm that bases only on two cross-sectional intensity images may be successfully used in clinical study of healthy eyes and
more » ... with diabetic maculopathy and branch retinal vein occlusion.
doi:10.1364/boe.6.002738 pmid:26309740 pmcid:PMC4541504 fatcat:usd5gsufebclplvnfeuzfhus5i