at the time of recruitment of follicles, is elevated due to diminished ovarian feedback of steroids and inhibins (Sherman Joop Schoemaker and Cornelis B.Lambalk and Korenman 1975; Lee et al., 1988; MacNaughton et al., Research Institute for Endocrinology, Reproduction and 1992). Inhibins are dimeric proteins that selectively inhibit Metabolism, Division of Reproductive Endocrinology and FSH secretion. Inhibin A is composed of a common α subunit Infertility, and a βA subunit, and inhibin B

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... ts of an α subunit Amsterdam, The Netherlands combined with a βB subunit. In recent years, studies on the differential secretion of inhibin A and inhibin B in the 1 To whom correspondence should be addressed at: Reproductive Endocrinology and Infertility, Department of Obstetrics and menstrual cycle (Groome et al., 1996) and in-situ hybridization Gynaecology, Vrije Universiteit Medical Centre, PO Box 7057, studies (Roberts et al., 1993) have shown that inhibin A 1007 MB Amsterdam, The Netherlands. appears to be primarily secreted by the mature follicle and