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Toward uncharted territory of cellular heterogeneity: advances and applications of single-cell RNA-seq
2020
Journal of Translational Genetics and Genomics
Among single-cell analysis technologies, single-cell RNA-seq (scRNA-seq) has been one of the front runners in technical inventions. Since its induction, scRNA-seq has been well received and undergone many fast-paced technical improvements in cDNA synthesis and amplification, processing and alignment of next generation sequencing reads, differentially expressed gene calling, cell clustering, subpopulation identification, and developmental trajectory prediction. scRNA-seq has been exponentially
doi:10.20517/jtgg.2020.51
pmid:34322662
pmcid:PMC8315474
fatcat:n6aeihgw2fewrirpvyuapmldcu