Substantial Improvement in a Nerve Conduction Study of Lymphoma-associated Demyelinating Neuropathy Treated by Intravenous Immunoglobulin and Chemotherapy

Tomoki Iemura, Akifumi Oba, Masashi Matsui, Chihiro Mano, Norihiro Kawabata, Yoshihito Horisawa, Yasuko Miyahara, Mitsuru Itoh
2019 Internal medicine (Tokyo. 1992)  
A 64-year-old woman with lymphoma-associated demyelinating neuropathy was treated by 6 cycles of R-CHOP with intravenous immunoglobulin in the first 2 cycles. We noted substantial improvement in the findings of a nerve conduction study (NCS) after the first cycle, followed by more protracted improvement during the second to sixth cycles. The improvement of the neurological symptoms paralleled the findings of the NCS. Our case provides important information for understanding the etiology and
more » ... mization of treatments for lymphoma-associated demyelinating neuropathy.
doi:10.2169/internalmedicine.0678-17 pmid:30101902 fatcat:qd5nlkg5rngqxfet727qudggey