A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit the original URL.
The file type is
Cellular cohesion provides tissue tension, which is then sensed by the cytoskeleton and decoded by the activity of mechano-transducers, such as the transcriptional cofactor Yap1, thereby enabling morphogenetic responses in multi-cellular organisms. How cell cohesion is regulated is nevertheless unclear. Here we show that, zebrafish epiboly progression, a prototypic morphogenetic event that depends on Yap activity, requires the maternal contribution of the proposed yap1 competitor vgll4a. Indoi:10.1101/2020.12.01.407478 fatcat:wtpy7zxxrfb6tgly572a2seipu