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The Relative Potencies of Thiopentone, Ketamine, Propanidid, Alphaxalone and Diazepam. A Statistical Study in Man
1980
Survey of Anesthesiology
Preserved Fulltext
The potency of five i.v. anaesthetics (thiopentone, ketamine, alphaxalone (Althesin), propanidid and diazepam) was studied by determining the dose required to produce unconsciousness in 50% (UD 50 ) and 95% (UD 95 ) of patients. UD 60 and UD 95 were determined using the probit method. The effect of age on the anaesthetic requirement has been studied also. Relative to thiopentone, the potency was alphaxalone 9.22, diazepam 5.24, ketamine 4.37 and propanidid 1.006.
doi:10.1097/00132586-198002000-00031
fatcat:h3yzbfic4jg5jo4gv62c4t72ym