Four known compounds have been isolated from the aerial parts of the Brazilian medicinal plant Pariparoba ( Pothomorphe umbellata). They were an alkaloid, a ‰avone, a dihydrocalcone, and a steroid. The chemical structures were established to be N benzoylmescaline, wogonin, uvangoletin, and b sitosterol glucoside using spectral methods. Among these compounds, the main component N benzoylmescaline showed signiˆcant antibacterial activity against Helicobacter pylori.