Membrane Reactor System for Parallel Continuous Screening and Characterisation of Biocatalysts

E. Lyagin, A. Drews, S. Bhattacharya, M. Kraume
2012 Chemical Engineering Transactions  
Reliable bioprocess design requires the estimation of "true" kinetic parameters, which should be the same for both scales - the lab-scale and the process scale. However, commercially available screening and characterisation systems are mostly operated in batch/fed-batch mode, which is not sufficient to describe the continuous operational mode that is typically used for native enzyme applications. So, a new concept of membrane based screening and characterisation system that enables physical
more » ... ntion of the dissolved catalyst is proposed and developed.
doi:10.3303/cet1227054 doaj:549df12a5add45d58007c6f21330e595 fatcat:yz6luh7gtnhhhjalinoy2nqbx4