A Case of Minocycline-induced Pneumonitis with Bronchial Asthma

Tetsuya Haruna, Yoshirou Mochizuki, Yasuharu Nakahara, Rieko Kawanami, Tetsuji Kawamura, Hisako Hashimoto, Kazunari Tsuyuguchi, Youko Matsushita
1994 The Japanese Journal of Thoracic Diseases  
We report a case of minocycline-induced pneumonitis. A 30-year-old woman was treated with minocycline for mycoplasma pneumonia of the right upper lobe. About 15 days after starting treatment, she developed a productive cough, stridor, and dyspnea. The chest X-ray film showed pulmonary infiltration in the left middle lung field. Based on the clinical history and the detection of eosinophilia in the bronchoalveolar fluid, drug-induced pneumonitis was suspected. Treatment with minocycline was
more » ... ntinued and prednisolone (20 mg/day) was started, after which her symptoms subsided and there was marked regression of the pulmonary infiltrates on chest X-ray films. The lymphocyte stimulation test for minocycline was negative, but the diagnosis was confirmed by a positive oral provocation test.
doi:10.11389/jjrs1963.32.671 fatcat:ckyxgtfmsbg7bcnjaggexte75q