A Case of Minocycline-induced Pneumonitis with Bronchial Asthma
ミノサイクリンにより発症した気管支ぜん息を伴う薬剤性肺臓炎の1例

Tetsuya Haruna, Yoshirou Mochizuki, Yasuharu Nakahara, Rieko Kawanami, Tetsuji Kawamura, Hisako Hashimoto, Kazunari Tsuyuguchi, Youko Matsushita
1994 The Japanese Journal of Thoracic Diseases  
We report a case of minocycline-induced pneumonitis. A 30-year-old woman was treated with minocycline for mycoplasma pneumonia of the right upper lobe. About 15 days after starting treatment, she developed a productive cough, stridor, and dyspnea. The chest X-ray film showed pulmonary infiltration in the left middle lung field. Based on the clinical history and the detection of eosinophilia in the bronchoalveolar fluid, drug-induced pneumonitis was suspected. Treatment with minocycline was
more » ... ntinued and prednisolone (20 mg/day) was started, after which her symptoms subsided and there was marked regression of the pulmonary infiltrates on chest X-ray films. The lymphocyte stimulation test for minocycline was negative, but the diagnosis was confirmed by a positive oral provocation test.
doi:10.11389/jjrs1963.32.671 fatcat:ckyxgtfmsbg7bcnjaggexte75q