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The Uniformed Services University's Surgical Critical Care Initiative (SC2i): Bringing Precision Medicine to the Critically Ill
<span title="2018-03-01">2018</span>
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<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/p2g77rcmcjaozgihldxgdylqs4" style="color: black;">Military medicine</a>
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Precision medicine endeavors to leverage all available medical data in pursuit of individualized diagnostic and therapeutic plans to improve patient outcomes in a cost-effective manner. Its promise in the field of critical care remains incompletely realized. The Department of Defense has a vested interest in advancing precision medicine for those sent into harm's way and specifically seeks means of individualizing care in the context of complex and highly dynamic combat clinical decision
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<a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/milmed/usx164">doi:10.1093/milmed/usx164</a>
<a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/29635571">pmid:29635571</a>
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... ments. Building on legacy research efforts conducted during the Afghanistan and Iraq conflicts, the Uniformed Service University (USU) launched the Surgical Critical Care Initiative (SC2i) in 2013 to develop clinical-and biomarker-driven Clinical Decision Support Systems (CDSS), with the goals of improving both patient-specific outcomes and resource utilization for conditions with a high risk of morbidity or mortality. Despite technical and regulatory challenges, this military-civilian partnership is beginning to deliver on the promise of personalized care, organizing and analyzing sizable, real-time medical data sets to support complex clinical decision-making across critical and surgical care disciplines. We present the SC2i experience as a generalizable template for the national integration of federal and non-federal research databanks to foster critical and surgical care precision medicine. PRESENTATION Presented as a poster at the 2016 Military Health System Research Symposium (abstract number MHSRS-16-0107) FUNDING Research activities leading to the development of this abstract were funded by the Department of Defense's Defense Health Program -Joint Program Committee 6/Combat Casualty Care (USUHS HT9404-13-1-0032 and HU0001-15-2-0001).
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