Objective: To investigate the clinical and pathological features of idiopathic membranous nephropathy (IMN) in young patients. were retrospectively analyzed, comparing to the 55 patients who were diagnosed with IMN as older patients during the same period in hospital. Analysis of the clinical and pathological features. Results: The morbidity of IMN in young patients is rising (accounted or IMN 26.7%), and have low proportion of hypertension, hyperglycemia and sclerosis glomeruli than IMN in

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... r patients (P Z 0.002; P Z 0.044; P < 0.0001). There were higher eGFR and LDL level than latter (P Z 0.027; P Z 0.038) but with low levels of T3 and T4 (P Z 0.03; P Z 0.034). Furthermore, there was less hyaline change of arteriole and arteriolar wall thickening than latter (P Z 0.027; P < 0.0001). Conclusion: IMN in young patients have low proportion of hypertension, hyperglycemia and sclerosis glomeruli than IMN in older patients, and with higher eGFR and LDL and lower levels of T3 and T4 than the latter. Furthermore, there is less hyaline change in arteriole and arteriolar wall thickening than latter. http://dx.