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Defining the Basis of Cyanine Phototruncation Enables a New Approach to Single-Molecule Localization Microscopy
2021
ACS Central Science
The light-promoted conversion of extensively used cyanine dyes to blue-shifted emissive products has been observed in various contexts. However, both the underlying mechanism and the species involved in this photoconversion reaction have remained elusive. Here we report that irradiation of heptamethine cyanines provides pentamethine cyanines, which, in turn, are photoconverted to trimethine cyanines. We detail an examination of the mechanism and substrate scope of this remarkable twocarbon
doi:10.1021/acscentsci.1c00483
fatcat:r2dmobhrybd4ja74njdypsnzmu