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Unpredictability of metabolism—the key role of metabolomics science in combination with next-generation genome sequencing
2011
Analytical and Bioanalytical Chemistry
Next-generation sequencing provides technologies which sequence whole prokaryotic and eukaryotic genomes in days, perform genome-wide association studies, chromatin immunoprecipitation followed by sequencing and RNA sequencing for transcriptome studies. An exponentially growing volume of sequence data can be anticipated, yet functional interpretation does not keep pace with the amount of data produced. In principle, these data contain all the secrets of living systems, the genotype-phenotype
doi:10.1007/s00216-011-4948-9
pmid:21556754
pmcid:PMC3098350
fatcat:pykytnqi65hm3iybb6cs6h6v6u