Multiple sclerosis (MS) is known as disseminated sclerosis by the British and the French as sclerosis in slabs. Affects mainly young female adults with multifactorial etiology and still little known. It is an inflammatory, chronic, demyelinating disease of the central nervous system, causing disseminated lesions or plaques in the white matter and spinal cord. The diagnosis is made by the McDonald criteria along with laboratory tests of cerebrospinal fluid, brain imaging and spinal magnetic

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... ance imaging and patient's medical history. The treatment is now performed by immunosuppressants and immunomodulators, where its sha-res are still little known, but are showing good results to MS patients. Therefore, this study aimed to describe the setting, immunopathology, diagnosis and treatment of MS. The method used was the literature research conducted in SciELO, BIREME, NCBI and PubMed sites. There are still few studies concerning this disease and that there are a little sketchy, it is necessary further research around the course and etiology of the disease.