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Signal Transduction Mediated by the Truncated trkB Receptor Isoforms, trkB.T1 and trkB.T2
1997
Journal of Neuroscience
The trkB family of transmembrane proteins serves as receptors for BDNF and NT-4/5. The family is composed of a tyrosine kinase-containing isoform as well as several alternatively spliced "truncated receptors" with identical extracellular ligandbinding domains but very small intracellular domains. The two best-characterized truncated trkB receptors, designated as trkB.T1 and trkB.T2, contain intracellular domains of only 23 and 21 amino acids, respectively. Although it is known that the tyrosine
doi:10.1523/jneurosci.17-08-02683.1997
pmid:9092589
fatcat:6m44de5mkzc7jcieg5d5ugwqfi